What's the evidence for naproxen?

There is only a small amount of evidence that naproxen can make your migraine attacks less severe.

Three small studies found that naproxen lessened the intensity of migraine headaches more than a dummy treatment (a placebo).^{1 2 3}

Two studies found that naproxen worked better than another treatment for migraine, called ergotamine.^{4 5} But nearly half the people withdrew from one of these studies before the end, so its results aren't reliable.⁵ Another study found no difference between naproxen and ergotamine.³

But none of these studies used the definition of migraine drawn up by a group of experts known as the International Headache Society. This makes the results of the studies less reliable because we cannot be sure that all the people in the studies actually got migraines.

For more details:

Read this information about the treatment in Clinical Evidence